Enhanced MRI relaxivity of aquated Gd3+ ions by carboxyphenylated water-dispersed graphene nanoribbons.

نویسندگان

  • Ayrat Gizzatov
  • Vazrik Keshishian
  • Adem Guven
  • Ayrat M Dimiev
  • Feifei Qu
  • Raja Muthupillai
  • Paolo Decuzzi
  • Robert G Bryant
  • James M Tour
  • Lon J Wilson
چکیده

The present study demonstrates that highly water-dispersed graphene nanoribbons dispersed by carboxyphenylated substituents and conjugated to aquated Gd(3+) ions can serve as a high-performance contrast agent (CA) for applications in T1- and T2-weighted magnetic resonance imaging (MRI) with relaxivity (r1,2) values outperforming currently-available clinical CAs by up to 16 times for r1 and 21 times for r2.

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عنوان ژورنال:
  • Nanoscale

دوره 6 6  شماره 

صفحات  -

تاریخ انتشار 2014